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St. Paul –Doctor’s Professional Building

280 Smith Avenue North Suite 600 St Paul, MN 55102

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Midwest Spine & Brain Institute Saint Paul Location

St. Paul –Doctor’s Professional Building

280 Smith Avenue North, Suite 600 St. Paul, MN 55102

Request Appointment

Expert Spine & Brain Care in St. Paul, Minnesota

Midwest Spine & Brain Institute’s St. Paul clinic is conveniently located in the Doctors Professional Building on the United Hospital campus, offering patients throughout St. Paul, West 7th, Highland Park, Mendota Heights, Woodbury, and the east metro area direct access to specialized spine and brain care – right in the heart of the city.
This hospital-affiliated setting allows patients to receive comprehensive neurological and spinal care in a trusted medical environment, supported by seamless coordination with United Hospital’s imaging and rehabilitation services.

New Project (34)
New Project (34)

Conditions We Treat

Our board-certified neurosurgeons, orthopedic spine surgeons, and advanced practice providers deliver expert diagnosis and treatment for a full range of spinal and neurological conditions, including:
  • Cervical and Lumbar Disc Disease
  • Spinal Stenosis and Nerve Compression
  • Scoliosis and Spinal Deformities
  • Complex Revision Spine Cases
  • Spinal Tumors and Lesions
  • Chronic Back and Neck Pain

Each consultation begins with a detailed evaluation of your medical history, imaging studies, and lifestyle goals.
Whenever possible, our specialists recommend non-surgical treatments first – such as physical therapy, pain management, and targeted injections.
If surgery becomes necessary, we provide clear explanations of every procedure, recovery timeline, and expected outcome, empowering you to make informed decisions about your care.

Meet Our St. Paul Specialists

Patients at the St. Paul clinic are treated by some of the Twin Cities’ most experienced spine and brain experts:
Stefano M. Sinicropi, M.D., F.A.A.O.S.
  • Orthopedic Spine Surgeon
  • Orthopedic Spine Surgeon
Dr. Sinicropi has performed thousands of advanced spine surgeries, helping patients across Minnesota and Wisconsin restore mobility and live pain-free lives through innovative, minimally invasive care.
Eduardo J. Perez, M.D., D.A.B.N.S.
  • Board-Certified Neurosurgeon
Dr. Perez focuses on advanced surgical and nonsurgical treatments for brain and spine conditions. His patient-centered approach ensures safe, effective care tailored to each individual’s needs.
David T. Chang, M.D., Ph.D., D.A.B.N.S.
  • Board-Certified Neurosurgeon
Dr. Chang combines world-class neurosurgical training with a compassionate, personalized approach, offering expertise in complex spine and brain surgery using the latest minimally invasive techniques.
Meysam A. Kebriaei, M.D., M.B.A., D.A.B.N.S.
  • Board-Certified Adult & Pediatric Neurosurgeon
Dr. Kebriaei provides expert care in brain and spine surgery, including disc replacement, vascular, and pediatric neurosurgery, offering personalized, research-based treatment plans for each patient.
Glenn R. Buttermann, M.D., M.S., F.A.A.O.S.
  • Orthopedic Spine Surgeon
Dr. Buttermann is globally recognized for his leadership in scoliosis and motion-preserving spine surgery. He integrates decades of research and innovation to provide optimal results for his patients.
Meet Our Providers

Why Patients Choose Our St. Paul Clinic

Patients in the Twin Cities choose Midwest Spine & Brain Institute for our blend of advanced expertise and personalized attention.

What makes our St. Paul location unique:

  • Hospital-based setting within the United Hospital campus for integrated, convenient care
  • Board-certified spine and brain specialists with decades of combined experience
  • Collaborative, multidisciplinary approach involving neurosurgeons, orthopedic surgeons, and advanced practice providers
  • Conservative-first philosophy emphasizing non-operative treatments whenever possible
  • Personalized patient experience with clear communication and accessible follow-up care
  • Central location with easy access from downtown St. Paul, I-35E, and I-94
While other larger regional practices may focus on higher patient volumes, our St. Paul clinic maintains a smaller, more personal setting, ensuring that every patient receives individualized attention and consistent care.

Directions & Parking

Our clinic is located in the Doctors Professional Building, Suite 600, directly connected to United Hospital.
Patients can enter from Smith Avenue North, with convenient ramp and surface parking available nearby.

  • Parking: Paid and patient-designated parking is available in the adjacent ramp connected to United Hospital.
  • Driving Directions: Easily accessible via I-35E, I-94, and West 7th Street - minutes from downtown St. Paul.

Nearby Midwest Spine Locations

We proudly serve patients across the Twin Cities metro and beyond:
  • Maple Grove, MN
  • Edina, MN
  • Stillwater, MN
  • Hudson, WI

Schedule Your Appointment

Take control of your spine and neurological health today.
Our compassionate team is ready to help you move better, feel better, and heal better – close to home.
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