Skull base surgery is surgery to remove tumors underneath the brain at the base of the skull. These tumors may be either malignant (cancerous) or benign (non-cancerous). Skull base surgery is very complex as there are multiple bones that form the base of the skull, the spinal cord passes through the skull base, and many blood vessels and nerves are present as well. Surgery is usually minimally invasive and access points include through the nose, through the mouth, or near the eyebrow. Because of the location and complexity of this type of surgery, other doctors may be involved in the procedure. These specialties may include radiologists, Ear Nose Throat (ENT) doctors, or maxillofacial surgeons.